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Arca moved from downtown Denver to much largert offices in Broomfield in appliedfor U.S. Food & Drug Administratiojn approval to sell the drug itcallse Gencaro, and reached a merger agreement in September with San Calif.-based Nuvelo. Gencaro is the commercial name proposed for thesubstancee bucindolol, a beta blocker Bristow has worked with for more than two Arca should be able to begin selling it, pendingb FDA approval, midway through 2009. Its acquisition of Nuvelo brings more experimental compounds into its drug pipeline and research labsin California.
Bristoaw was the primary founder and chierf medical officerat Westminster-based , which developee drugs to treat cardiovascular disorders. It appeared poisefd to have success with two compoundsz when acquired itfor $2.5 billion in late 2006. www.level3.com James Crowe, founder and longtime CEO of Broomfield-based Leveol 3 Communications, has taken on a more central role with the compan following a rough year and the departure of one of itsothedr founders.
Kevin O’Hara, one of the founders who helped Crow launch Level 3in 1997, left the fiber-optic network and servicez company in March 2008 afte r it continued to struggle with its handling of new customer account s in the wake of six majorr acquisitions in the previous two years. The move left Level 3 withoutr a COOand president, duties Crowe since has filled. Crowd long has touted the increasingly integral role that Leve l3 and, in general, broadbanrd connections and high-tech services will play in a digita economy.
Now, his hands-on leadershiop will be more key tothe company’s Crowe has led Level 3 since it spun off from Omaha-baser construction giant It was the second compangy Crowe launched as a fiber-optic wholesale startup from He built with Kiewit backing, starting in and sold it to WorldCom for $14.3 billionh three years later, a deal that sparked the late-1990w telecom boom. www.dishnetwork.com Charlie Ergen’zs name has been associated for a long timewith direct-to-homew satellite broadcasting and with his company’xs Dish Network programming. But in the past Ergen’s business interests have grown into three separatwe companies charting different coursesfrom Englewood.
At the star of the year, Ergen’s company splift into a stand-alone , a 13.8 million-subscriber satellit e TV company, and , a companty developing set-top boxes for the paid TV industry and othedrtechnology products. Dish Network but ultimately lost, its bid to be the satellite TV partneffor nationally. It was a costly loss to largerfrival , coming afterd Dish Network posted its firsty quarterly loss of subscribers. Ergen’s newest company, LLC, spen t $712 million in early 2008 buying the rights to frequencie s in168 U.S.
cities missing only Los Angeles, San Francisco, Philadelphia, New York City and Bostob among major mediamarkets — that are expected to be used to broadcasgt video to mobile phones. EchoStar had a contract to beam such mobile video servicesinto China, but that deal appeare to be on hold. www.ibm.comm Larry Longseth, head of Colorad o operations for , is seeing green. One of the largest ­­— if not the largest — corporate effortds in Colorado to adopt more environmentally friendly energy consumptiojn is taking place onthe Armonk, N.Y.-based company’s Bouldedr campus.